An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program

In this study, we present an effective model All-Trans Retinoic Acid (ATRA)-induced differentiation of HL-60 cells. The model describes reinforcing feedback between an ATRA-inducible signalsome complex involving many proteins including Vav1, a guanine nucleotide exchange factor, and the activation o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tasseff, Ryan, Jensen, Holly A., Congleton, Johanna, Dai, David, Rogers, Katharine V., Sagar, Adithya, Bunaciu, Rodica P., Yen, Andrew, Varner, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662654/
https://ncbi.nlm.nih.gov/pubmed/29085021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14523-5
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