The Src-Family Kinase Inhibitor PP2 Rescues Inducible Differentiation Events in Emergent Retinoic Acid-Resistant Myeloblastic Leukemia Cells

Retinoic acid is an embryonic morphogen and dietary factor that demonstrates chemotherapeutic efficacy in inducing maturation in leukemia cells. Using HL60 model human myeloid leukemia cells, where all-trans retinoic acid (RA) induces granulocytic differentiation, we developed two emergent RA-resist...

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Bibliografiske detaljer
Main Authors: Jensen, Holly A., Styskal, Lauren E., Tasseff, Ryan, Bunaciu, Rodica P., Congleton, Johanna, Varner, Jeffrey D., Yen, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598855/
https://ncbi.nlm.nih.gov/pubmed/23554907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058621
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