RRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

All-trans-retinoic acid (RA) is known to induce terminal granulocytic differentiation and cell cycle arrest of HL-60 cells. Responding to an RA-induced cytosolic signaling machine, c-Raf translocates to the nucleus, providing propulsion for RA-induced differentiation. This novel mechanism is not und...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Wallace, Aaron S., Supnick, Harrison T., Bunaciu, Rodica P., Yen, Andrew
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216806/
https://ncbi.nlm.nih.gov/pubmed/27331409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10136
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