LRH-1 is a critical determinant of methyl-pool metabolism

Balance of labile methyl groups (choline, methionine, betaine, and folate) is important for normal liver function. Quantitatively, a significant use of labile methyl groups is in production of phosphatidylcholines (PCs), which are ligands for the nuclear receptor LRH-1. We studied the role of LRH-1...

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Bibliographic Details
Published in:Hepatology
Main Authors: Wagner, Martin, Choi, Sungwoo, Panzitt, Katrin, Mamrosh, Jennifer L., Lee, Jae Man, Zaufel, Alex, Xiao, Rui, Wooton-Kee, Ruth, Ståhlman, Marcus, Newgard, Christopher B., Borén, Jan, Moore, David D.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662191/
https://ncbi.nlm.nih.gov/pubmed/26267291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28124
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