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LRH-1 is a critical determinant of methyl-pool metabolism
Balance of labile methyl groups (choline, methionine, betaine, and folate) is important for normal liver function. Quantitatively, a significant use of labile methyl groups is in production of phosphatidylcholines (PCs), which are ligands for the nuclear receptor LRH-1. We studied the role of LRH-1...
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| Udgivet i: | Hepatology |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5662191/ https://ncbi.nlm.nih.gov/pubmed/26267291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28124 |
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