Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer’s Disease: The role of APP

Overexpression of the amyloid precursor protein (APP)gene on chromosome 21 in Down syndrome (DS) has been linked to increased brain amyloid levels and early-onset Alzheimer’s disease (AD). An elderly man with phenotypic DS and partial trisomy of chromosome 21 (PT21) lacked triplication of APP afford...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Alzheimers Dis
Asıl Yazarlar: Doran, Eric, Keator, David, Head, Elizabeth, Phelan, Michael J., Kim, Ron, Totoiu, Minodora, Barrio, Jorge R., Small, Gary W., Potkin, Steven G., Lott, Ira T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662115/
https://ncbi.nlm.nih.gov/pubmed/27983553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160836
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller