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Enhanced sleep reverses memory deficits and underlying pathology in drosophila models of Alzheimer's disease
To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein and Beta-secretase (APP:BACE), or in flies expressing human tau. The ubiquitous expression of APP:BACE or human tau disr...
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| Publicado no: | Neurobiol Sleep Circadian Rhythms |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5662006/ https://ncbi.nlm.nih.gov/pubmed/29094110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbscr.2016.09.001 |
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