Enhanced sleep reverses memory deficits and underlying pathology in drosophila models of Alzheimer's disease

To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein and Beta-secretase (APP:BACE), or in flies expressing human tau. The ubiquitous expression of APP:BACE or human tau disr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurobiol Sleep Circadian Rhythms
Päätekijät: Dissel, Stephane, Klose, Markus, Donlea, Jeff, Cao, Lijuan, English, Denis, Winsky-Sommerer, Raphaelle, van Swinderen, Bruno, Shaw, Paul J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662006/
https://ncbi.nlm.nih.gov/pubmed/29094110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbscr.2016.09.001
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia