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Enhanced sleep reverses memory deficits and underlying pathology in drosophila models of Alzheimer's disease
To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein and Beta-secretase (APP:BACE), or in flies expressing human tau. The ubiquitous expression of APP:BACE or human tau disr...
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| Published in: | Neurobiol Sleep Circadian Rhythms |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5662006/ https://ncbi.nlm.nih.gov/pubmed/29094110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbscr.2016.09.001 |
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