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Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson’s substantia nigra
Iron deposition in Parkinson’s disease (PD) is a potential disease-modifying target. We previously showed that supplementation of the iron-exporter, ceruloplasmin, selectively corrected nigral iron elevation in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model. Ceruloplasmin delivers iro...
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| Publicado no: | Signal Transduct Target Ther |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661661/ https://ncbi.nlm.nih.gov/pubmed/29263898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.15 |
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