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Inhibiting cancer cell hallmark features through nuclear export inhibition
Treating cancer through inhibition of nuclear export is one of the best examples of basic research translation into clinical application. Nuclear export factor chromosomal region maintenance 1 (CRM1; Xpo1 and exportin-1) controls cellular localization and function of numerous proteins that are criti...
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| Publicado no: | Signal Transduct Target Ther |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661660/ https://ncbi.nlm.nih.gov/pubmed/29263896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.10 |
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