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Inhibiting cancer cell hallmark features through nuclear export inhibition
Treating cancer through inhibition of nuclear export is one of the best examples of basic research translation into clinical application. Nuclear export factor chromosomal region maintenance 1 (CRM1; Xpo1 and exportin-1) controls cellular localization and function of numerous proteins that are criti...
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| Izdano u: | Signal Transduct Target Ther |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661660/ https://ncbi.nlm.nih.gov/pubmed/29263896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.10 |
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