Functional analysis of BRCT missense mutations in BRCA1-mutated Chinese Han familial breast cancer

Breast cancer 1 (BRCA1) is one of the most common tumor suppressor genes in breast cancer. The BRCT domain of BRCA1 has been shown to have a critical role in tumor suppression. In a previous study, two de novo BRCT missense mutations of BRCA1, G1763V and L1786P were identified from Chinese females w...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Zhang, Hong, Li, Linsen, Wang, Yuxia, Yin, C. Cameron, Xie, Yuntao, Liu, Xijuan, Ding, Huirong, Tian, Zhihua, Shen, Jing, He, Long, Xia, Miaoran, Ma, Xi, Wu, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661407/
https://ncbi.nlm.nih.gov/pubmed/29113215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7003
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