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Biomechanical Regulation of Drug Sensitivity in an Engineered Model of Human Tumor

Predictive testing of anticancer drugs remains a challenge. Bioengineered systems, designed to mimic key aspects of the human tumor microenvironment, are now improving our understanding of cancer biology and facilitating clinical translation. We show that mechanical signals have major effects on can...

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Dettagli Bibliografici
Pubblicato in:Biomaterials
Autori principali: Marturano-Kruik, A., Villasante, A., Yaeger, K., Ambati, S. R., Chramiec, A., Raimondi, M.T, Vunjak-Novakovic, G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660643/
https://ncbi.nlm.nih.gov/pubmed/29040875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.10.020
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