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Biomechanical Regulation of Drug Sensitivity in an Engineered Model of Human Tumor

Predictive testing of anticancer drugs remains a challenge. Bioengineered systems, designed to mimic key aspects of the human tumor microenvironment, are now improving our understanding of cancer biology and facilitating clinical translation. We show that mechanical signals have major effects on can...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Marturano-Kruik, A., Villasante, A., Yaeger, K., Ambati, S. R., Chramiec, A., Raimondi, M.T, Vunjak-Novakovic, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660643/
https://ncbi.nlm.nih.gov/pubmed/29040875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.10.020
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