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Biomechanical Regulation of Drug Sensitivity in an Engineered Model of Human Tumor

Predictive testing of anticancer drugs remains a challenge. Bioengineered systems, designed to mimic key aspects of the human tumor microenvironment, are now improving our understanding of cancer biology and facilitating clinical translation. We show that mechanical signals have major effects on can...

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Detalles Bibliográficos
Publicado en:Biomaterials
Autores principales: Marturano-Kruik, A., Villasante, A., Yaeger, K., Ambati, S. R., Chramiec, A., Raimondi, M.T, Vunjak-Novakovic, G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660643/
https://ncbi.nlm.nih.gov/pubmed/29040875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.10.020
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