Dexamethasone and Monophosphoryl Lipid A Induce a Distinctive Profile on Monocyte-Derived Dendritic Cells through Transcriptional Modulation of Genes Associated With Essential Processes of the Immune Response

There is growing interest in the use of tolerogenic dendritic cells (tolDCs) as a potential target for immunotherapy. However, the molecular bases that drive the differentiation of monocyte-derived DCs (moDCs) toward a tolerogenic state are still poorly understood. Here, we studied the transcription...

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Udgivet i:Front Immunol
Main Authors: García-González, Paulina A., Schinnerling, Katina, Sepúlveda-Gutiérrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Bárbara, Larrondo, Milton L., Aravena, Octavio, Molina, María C., Catalán, Diego, Thomas, Ranjeny, Verdugo, Ricardo A., Aguillón, Juan C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660598/
https://ncbi.nlm.nih.gov/pubmed/29109727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01350
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