Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features

Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases, such as rheumatoid arthritis (RA). Here, we characterize monocyte-derived TolDCs from RA patients modulated with dexamethasone and activated with monophosphoryl lipid A (MPLA), referred to as MPLA-tDCs, in t...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: García-González, Paulina A., Schinnerling, Katina, Sepúlveda-Gutiérrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Bárbara, Molina, María Carmen, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Óscar, Catalán, Diego Francisco, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A., Aguillón, Juan C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2016
נושאים:
Immunology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078319/
https://ncbi.nlm.nih.gov/pubmed/27826300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00458
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