Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4(+) T Cells

Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs (tDCs)] to exert immunomodulatory effects on naive and memory CD4(+) T cells...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Maggi, Jaxaira, Schinnerling, Katina, Pesce, Bárbara, Hilkens, Catharien M., Catalán, Diego, Aguillón, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027201/
https://ncbi.nlm.nih.gov/pubmed/27698654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00359
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