Foot-and-Mouth Disease (FMD) Virus 3C Protease Mutant L127P: Implications for FMD Vaccine Development

The foot-and-mouth disease virus (FMDV) afflicts livestock in more than 80 countries, limiting food production and global trade. Production of foot-and-mouth disease (FMD) vaccines requires cytosolic expression of the FMDV 3C protease to cleave the P1 polyprotein into mature capsid proteins, but the...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Puckette, Michael, Clark, Benjamin A., Smith, Justin D., Turecek, Traci, Martel, Erica, Gabbert, Lindsay, Pisano, Melia, Hurtle, William, Pacheco, Juan M., Barrera, José, Neilan, John G., Rasmussen, Max
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660475/
https://ncbi.nlm.nih.gov/pubmed/28878081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00924-17
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