Receptor binding site-deleted foot-and-mouth disease (FMD) virus protects cattle from FMD.

Binding of foot-and-mouth disease virus (FMDV) to cells requires an arginine-glycine-aspartic acid (RGD) sequence in the capsid protein VP1. We have genetically engineered an FMDV in which these three amino acids have been deleted, producing a virus particle which is unable to bind to cells. Cattle...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	McKenna, T S, Lubroth, J, Rieder, E, Baxt, B, Mason, P W
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189442/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7637023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5787-5790.1995
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