Characterization of synthetic foot-and-mouth disease virus provirions separates acid-mediated disassembly from infectivity.

One of the final steps in the maturation of foot-and-mouth disease virus (FMDV) is cleavage of the VP0 protein to produce VP4 and VP2. The mechanism of this cleavage is unknown, but it is thought to function in stabilizing the virus particle and priming it for infecting cells. To investigate the cle...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Knipe, T, Rieder, E, Baxt, B, Ward, G, Mason, P W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.2851-2856.1997
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