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Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB(2) Receptors

The mechanism of action of cannabidiol (CBD), the main non-psychotropic component of Cannabis sativa L., is not completely understood. First assumed that the compound was acting via cannabinoid CB(2) receptors (CB(2)Rs) it is now suggested that it interacts with non-cannabinoid G-protein-coupled rec...

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Библиографические подробности
Опубликовано в: :Front Pharmacol
Главные авторы: Martínez-Pinilla, Eva, Varani, Katia, Reyes-Resina, Irene, Angelats, Edgar, Vincenzi, Fabrizio, Ferreiro-Vera, Carlos, Oyarzabal, Julen, Canela, Enric I., Lanciego, José L., Nadal, Xavier, Navarro, Gemma, Borea, Pier Andrea, Franco, Rafael
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660261/
https://ncbi.nlm.nih.gov/pubmed/29109685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00744
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