Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB(2) Receptors

The mechanism of action of cannabidiol (CBD), the main non-psychotropic component of Cannabis sativa L., is not completely understood. First assumed that the compound was acting via cannabinoid CB(2) receptors (CB(2)Rs) it is now suggested that it interacts with non-cannabinoid G-protein-coupled rec...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Martínez-Pinilla, Eva, Varani, Katia, Reyes-Resina, Irene, Angelats, Edgar, Vincenzi, Fabrizio, Ferreiro-Vera, Carlos, Oyarzabal, Julen, Canela, Enric I., Lanciego, José L., Nadal, Xavier, Navarro, Gemma, Borea, Pier Andrea, Franco, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660261/
https://ncbi.nlm.nih.gov/pubmed/29109685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00744
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