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Ocular antigen does not cause disease unless presented in the context of inflammation

Ocular antigens are sequestered behind the blood-retina barrier and the ocular environment protects ocular tissues from autoimmune attack. The signals required to activate autoreactive T cells and allow them to cause disease in the eye remain in part unclear. In particular, the consequences of perip...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Voigt, Valentina, Wikstrom, Matthew E., Kezic, Jelena M., Schuster, Iona S., Fleming, Peter, Makinen, Kimmo, Daley, Stephen R., Andoniou, Christopher E., Degli-Esposti, Mariapia A., Forrester, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660195/
https://ncbi.nlm.nih.gov/pubmed/29079770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14618-z
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