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Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells

Gene delivery to primary human cells is a technology of critical interest to both life science research and therapeutic applications. However, poor efficiencies in gene transfer and undesirable safety profiles remain key limitations in advancing this technology. Here, we describe a materials-based a...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Khalil, Andrew S., Yu, Xiaohua, Xie, Angela W., Fontana, Gianluca, Umhoefer, Jennifer M., Johnson, Hunter J., Hookway, Tracy A., McDevitt, Todd C., Murphy, William L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660152/
https://ncbi.nlm.nih.gov/pubmed/29079806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14153-x
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