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Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells

Gene delivery to primary human cells is a technology of critical interest to both life science research and therapeutic applications. However, poor efficiencies in gene transfer and undesirable safety profiles remain key limitations in advancing this technology. Here, we describe a materials-based a...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Khalil, Andrew S., Yu, Xiaohua, Xie, Angela W., Fontana, Gianluca, Umhoefer, Jennifer M., Johnson, Hunter J., Hookway, Tracy A., McDevitt, Todd C., Murphy, William L.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660152/
https://ncbi.nlm.nih.gov/pubmed/29079806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14153-x
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