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Nanostructured Mineral Coatings Stabilize Proteins for Therapeutic Delivery

Proteins tend to lose their biological activity due to their fragile structural conformation during formulation, storage and delivery. Thus, the inability to stabilize proteins in controlled-release systems represents a major obstacle in drug delivery. Here we present a bone mineral inspired protein...

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Detalhes bibliográficos
Publicado no:Adv Mater
Main Authors: Yu, Xiaohua, Biedrzycki, Adam H., Khalil, Andrew S, Hess, Dalton, Umhoefer, Jennifer M., Markel, Mark D., Murphy, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628619/
https://ncbi.nlm.nih.gov/pubmed/28675637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201701255
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