A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria

Mycobacterium tuberculosis has the ability to survive inside macrophages under acid-nitrosative stress. M. tuberculosis Rv1685c and its ortholog in M. smegmatis, MSMEG_3765, are induced on exposure to acid-nitrosative stress. Both genes are annotated as TetR transcriptional regulators, a family of p...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Perrone, Filomena, De Siena, Barbara, Muscariello, Lidia, Kendall, Sharon L., Waddell, Simon J., Sacco, Margherita
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660060/
https://ncbi.nlm.nih.gov/pubmed/29109706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02039
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