Patient-derived xenografts undergo murine-specific tumor evolution

Patient-derived xenografts (PDXs) have become a prominent cancer model system, as they are presumed to faithfully represent the genomic features of primary tumors. Here we monitored the dynamics of copy number alterations (CNAs) in 1,110 PDX samples across 24 cancer types. We observed rapid accumula...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Ben-David, Uri, Ha, Gavin, Tseng, Yuen-Yi, Greenwald, Noah F., Oh, Coyin, Shih, Juliann, McFarland, James M., Wong, Bang, Boehm, Jesse S., Beroukhim, Rameen, Golub, Todd R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659952/
https://ncbi.nlm.nih.gov/pubmed/28991255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3967
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados