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The landscape of chromosomal aberrations in breast cancer mouse models reveals driver-specific routes to tumorigenesis
Aneuploidy and copy-number alterations (CNAs) are a hallmark of human cancer. Although genetically engineered mouse models (GEMMs) are commonly used to model human cancer, their chromosomal landscapes remain underexplored. Here we use gene expression profiles to infer CNAs in 3,108 samples from 45 m...
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| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932194/ https://ncbi.nlm.nih.gov/pubmed/27374210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12160 |
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