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Antimicrobial Peptides are Degraded by the Cytosolic Proteases of Human Erythrocytes

Well-studied and promising antimicrobial peptides (AMPs), with potent bactericidal activity, in vitro, have yet to have a significant impact in human medicine beyond topical applications. We previously showed that interactions of AMPs with concentrated human erythrocytes inhibit many of them, and su...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteurs principaux: Starr, Charles G., Wimley, William C.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659893/
https://ncbi.nlm.nih.gov/pubmed/28912099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2017.09.008
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