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Degradation of naturally occurring and engineered antimicrobial peptides by proteases

We hypothesized that current antimicrobial peptides should be susceptible to proteolytic digestion. The antimicrobial peptides: Griffithinsin, RC-101, LL-37, LSA-5, PSC-RANTES and DJ007 were degraded by commercially available proteases. Two different species of anaerobic vaginal flora, Prevotella bi...

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Main Authors: Moncla, Bernard J., Pryke, Kara, Rohan, Lisa Cencia, Graebing, Phillip W.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354962/
https://ncbi.nlm.nih.gov/pubmed/22611520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/abb.2011.26059
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