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A quadratically regularized functional canonical correlation analysis for identifying the global structure of pleiotropy with NGS data

Investigating the pleiotropic effects of genetic variants can increase statistical power, provide important information to achieve deep understanding of the complex genetic structures of disease, and offer powerful tools for designing effective treatments with fewer side effects. However, the curren...

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Lin, Nan, Zhu, Yun, Fan, Ruzong, Xiong, Momiao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659802/
https://ncbi.nlm.nih.gov/pubmed/29040274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005788
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