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Canonical Correlation Analysis for Gene-Based Pleiotropy Discovery

Genome-wide association studies have identified a wealth of genetic variants involved in complex traits and multifactorial diseases. There is now considerable interest in testing variants for association with multiple phenotypes (pleiotropy) and for testing multiple variants for association with a s...

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Detalhes bibliográficos
Main Authors: Seoane, Jose A., Campbell, Colin, Day, Ian N. M., Casas, Juan P., Gaunt, Tom R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199483/
https://ncbi.nlm.nih.gov/pubmed/25329069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003876
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