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GATOR1 regulates nitrogenic cataplerotic reactions of the mitochondrial TCA cycle
The GATOR1/SEACIT complex consisting of Iml1-Npr2-Npr3 inhibits Target of Rapamycin Complex 1 (TORC1) in response to amino acid insufficiency. In glucose medium, Saccharomyces cerevisiae mutants lacking the function of this complex grow poorly in the absence of amino acid supplementation, despite ha...
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| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659745/ https://ncbi.nlm.nih.gov/pubmed/28920930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2478 |
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