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GATOR1 regulates nitrogenic cataplerotic reactions of the mitochondrial TCA cycle
The GATOR1/SEACIT complex consisting of Iml1-Npr2-Npr3 inhibits Target of Rapamycin Complex 1 (TORC1) in response to amino acid insufficiency. In glucose medium, Saccharomyces cerevisiae mutants lacking the function of this complex grow poorly in the absence of amino acid supplementation, despite ha...
Gorde:
| Argitaratua izan da: | Nat Chem Biol |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659745/ https://ncbi.nlm.nih.gov/pubmed/28920930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2478 |
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