Epicutaneous Tolerance Induction to a Bystander Antigen Abrogates Colitis and Ileitis in Mice

BACKGROUND: Although inflammatory bowel disease (IBD) is a failure in maintaining tolerance to the intestinal microbiota, few studies have investigated the use of immunologic tolerance as a treatment approach for IBD. We hypothesized that induction of immune tolerance at a distal site could suppress...

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Veröffentlicht in:Inflamm Bowel Dis
Hauptverfasser: Dunkin, David, Berin, M. Cecilia, Mondoulet, Lucie, Tobar, Steven, Yeretssian, Garabet, Tordesillas, Leticia, Iuga, Alina, Larcher, Thibaut, Guillespie, Virginia, Benhamou, Pierre-Henri, Colombel, Jean-Frederic, Sampson, Hugh A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659741/
https://ncbi.nlm.nih.gov/pubmed/29019858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001273
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