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Bifunctional aryliodonium salts for highly efficient radioiodination and astatination of antibodies

In this report we describe the development of an alternative approach to arylstannane chemistry for radiolabeling antibodies with radioiodine or astatine based on aryliodonium salts precursors. Bifunctional aryliodonium salts were designed and tested for the synthesis of (125)I and (211)At labeled p...

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Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem
Hoofdauteurs: Guérard, F., Navarro, L., Lee, Y.-S., Roumesy, A., Alliot, C., Chérel, M., Brechbiel, M.W., Gestin, J.-F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659727/
https://ncbi.nlm.nih.gov/pubmed/28964629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.09.022
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