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Bifunctional aryliodonium salts for highly efficient radioiodination and astatination of antibodies

In this report we describe the development of an alternative approach to arylstannane chemistry for radiolabeling antibodies with radioiodine or astatine based on aryliodonium salts precursors. Bifunctional aryliodonium salts were designed and tested for the synthesis of (125)I and (211)At labeled p...

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Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: Guérard, F., Navarro, L., Lee, Y.-S., Roumesy, A., Alliot, C., Chérel, M., Brechbiel, M.W., Gestin, J.-F.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659727/
https://ncbi.nlm.nih.gov/pubmed/28964629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.09.022
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