CFTR Influences Beta Cell Function and Insulin Secretion Through Non-Cell Autonomous Exocrine-Derived Factors

Although β-cell dysfunction in cystic fibrosis (CF) leads to diabetes, the mechanism by which the cystic fibrosis transmembrane conductance regulator (CFTR) channel influences islet insulin secretion remains debated. We investigated the CFTR-dependent islet-autonomous mechanisms affecting insulin se...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Sun, Xingshen, Yi, Yaling, Xie, Weiliang, Liang, Bo, Winter, Michael C., He, Nan, Liu, Xiaoming, Luo, Meihui, Yang, Yu, Ode, Katie Larson, Uc, Aliye, Norris, Andrew W., Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659686/
https://ncbi.nlm.nih.gov/pubmed/28977592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00187
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