Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone

The androgen receptor (AR) plays a critical role in the development of castration-resistant prostate cancer (CRPC) as well as in the resistance to the second-generation AR antagonist enzalutamide and the selective inhibitor of cytochrome P450 17A1 (CYP17A1) abiraterone. Novel agents targeting AR may...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Endocrinology
Autors principals: Masoodi, Khalid Z., Eisermann, Kurtis, Yang, Zhenyu, Dar, Javid A., Pascal, Laura E., Nguyen, Minh, O’Malley, Katherine, Parrinello, Erica, Feturi, Firuz G., Kenefake, Alex N., Nelson, Joel B., Johnston, Paul A., Wipf, Peter, Wang, Zhou
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2017
Matèries:
Special Section: Targeting and Regulation of Hormone Signaling
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659684/
https://ncbi.nlm.nih.gov/pubmed/28977599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00408
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars