Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma

The contributions of coding mutations to tumorigenesis are relatively well known; however, little is known about somatic alterations in noncoding DNA. Here we describe GECCO (Genomic Enrichment Computational Clustering Operation) to analyze somatic noncoding alterations in 308 pancreatic ductal aden...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Feigin, Michael E., Garvin, Tyler, Bailey, Peter, Waddell, Nicola, Chang, David K., Kelley, David R., Shuai, Shimin, Gallinger, Steven, McPherson, John D., Grimmond, Sean M., Khurana, Ekta, Stein, Lincoln D., Biankin, Andrew V., Schatz, Michael C., Tuveson, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659388/
https://ncbi.nlm.nih.gov/pubmed/28481342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3861
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