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LARVA: an integrative framework for large-scale analysis of recurrent variants in noncoding annotations

In cancer research, background models for mutation rates have been extensively calibrated in coding regions, leading to the identification of many driver genes, recurrently mutated more than expected. Noncoding regions are also associated with disease; however, background models for them have not be...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Lochovsky, Lucas, Zhang, Jing, Fu, Yao, Khurana, Ekta, Gerstein, Mark
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787796/
https://ncbi.nlm.nih.gov/pubmed/26304545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv803
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