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Single-cell Visualization of Chromosome Transcriptional Territories by RNA-paint

We developed a FISH-based method to directly assess chromosome-wide transcriptional activity, thereby enabling the visualization of the actively transcribed fraction of a chromosome at the single-cell level. We applied this method to probe the activity of X-chromosomes and its instability in the con...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Vallot, Céline, Rougeulle, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659369/
https://ncbi.nlm.nih.gov/pubmed/29082283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.1914
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