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Tuning parameters of dimensionality reduction methods for single-cell RNA-seq analysis

BACKGROUND: Many computational methods have been developed recently to analyze single-cell RNA-seq (scRNA-seq) data. Several benchmark studies have compared these methods on their ability for dimensionality reduction, clustering, or differential analysis, often relying on default parameters. Yet, gi...

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Publicat a:Genome Biol
Autors principals: Raimundo, Felix, Vallot, Celine, Vert, Jean-Philippe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444048/
https://ncbi.nlm.nih.gov/pubmed/32831127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02128-7
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