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PTEN in the maintenance of genome integrity: From DNA replication to chromosome segregation

Faithful DNA replication and accurate chromosome segregation are the key machineries of genetic transmission. Disruption of these processes represents a hallmark of cancer and often results from loss of tumor suppressors. PTEN is an important tumor suppressor frequently mutated or deleted in human c...

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Publicat a:Bioessays
Autors principals: Hou, Sheng-Qi, Ouyang, Meng, Brandmaier, Andrew, Hao, Hongbo, Shen, Wen H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659364/
https://ncbi.nlm.nih.gov/pubmed/28891157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700082
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