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PTEN at the interface of immune tolerance and tumor suppression
BACKGROUND: PTEN is well known to function as a tumor suppressor that antagonizes oncogenic signaling and maintains genomic stability. The PTEN gene is frequently deleted or mutated in human cancers and the wide cancer spectrum associated with PTEN deficiency has been recapitulated in a variety of m...
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| Publicado no: | Front Biol (Beijing) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841164/ https://ncbi.nlm.nih.gov/pubmed/29527223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-017-1443-5 |
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