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PTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis
Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome segregation to ensure mitotic fidelity. Tumour suppressor PTEN has multiple functions in maintaining genome stability. Here we report an essential role of PTEN in mitosis through r...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980451/ https://ncbi.nlm.nih.gov/pubmed/27492783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12355 |
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