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Brain Injury-Induced Synaptic Reorganization in Hilar Inhibitory Neurons Is Differentially Suppressed by Rapamycin

Following traumatic brain injury (TBI), treatment with rapamycin suppresses mammalian (mechanistic) target of rapamycin (mTOR) activity and specific components of hippocampal synaptic reorganization associated with altered cortical excitability and seizure susceptibility. Reemergence of seizures aft...

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Détails bibliographiques
Publié dans:eNeuro
Auteurs principaux: Butler, Corwin R., Boychuk, Jeffery A., Smith, Bret N.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659239/
https://ncbi.nlm.nih.gov/pubmed/29085896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0134-17.2017
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